Recent Publications by UAB FacultyQuality Analysis of YouTube Videos Presenting Shoulder Exercises after Breast Cancer Surgery June 24, 2022CONCLUSION: The quality of YouTube videos of recommended exercises post-BC surgery is high and can be a translational activity to improve patients' behavior. Health institutions and NGOs, with higher popularity levels than academic institutions, should consider this information when implementing new policies focused on video quality which can contribute to adaptive behavior in patients. Alvaro Manuel Rodriguez RodriguezEffect of Nano-Curcumin on Radiotherapy-Induced Skin Reaction in Breast Cancer Patients: A Randomized, Triple-Blind, Placebo-Controlled Trial June 24, 2022CONCLUSIONS: In general, it was found that administration of nano-curcumin could alleviate radiation-induced skin toxicity of breast cancer patients, but this effect was not significant. Tamara TalakeshDefinitive treatment choice among Black immigrants with prostate cancer: Analysis of patient surveys distributed at a single safety-net institution June 24, 2022CONCLUSIONS: In our study of a majority-Black population, we found that patients born in the United States were less likely than their foreign counterparts to opt for surgery, as previous studies have shown. The choice of definitive treatment modality for Black men with intermediate risk PCa was found to be influenced by age at diagnosis […] John R HeardInterventional oncology procedures for breast cancer metastatic disease: current role and clinical applications June 24, 2022Worldwide, breast cancer constitutes the most common malignant neoplasm among females, impacting 2.1 million women annually. Interventional oncology techniques have been recently added as an additional therapeutic and palliative alternative in breast cancer metastatic disease, concerning mainly osseous, liver, and lung metastasis. In the current literature, there are reports of promising results and documented efficacy […] Dimitrios K FilippiadisCardiovascular Toxicities with Chimeric Antigen Receptor T-cell Therapy June 24, 2022Chimeric antigen receptor (CAR) T-cell therapy has shown remarkable efficacy in treating highly refractory and relapsing hematological malignancies in pediatric and adult patients. However, this promising therapy is limited by severe and potentially life-threatening toxicities. Cytokine release syndrome (CRS) is the most commonly observed of these toxicities. The cardiovascular manifestations of CRS include tachycardia, hypotension, […] Jashan GillMedulloblastoma and the DNA Damage Response June 24, 2022Medulloblastoma (MB) is the most common malignant brain tumor in children with standard of care consisting of surgery, radiation, and chemotherapy. Recent molecular profiling led to the identification of four molecularly distinct MB subgroups - Wingless (WNT), Sonic Hedgehog (SHH), Group 3, and Group 4. Despite genomic MB characterization and subsequent tumor stratification, clinical treatment […] Leon F McSwainImpact of community-based exercise on fatigue in early breast cancer survivors: identifying potential determinants of change June 24, 2022CONCLUSION: Community-based exercise appears beneficial for alleviating fatigue in EBCS. These improvements may be driven by parallel improvements in psychosocial outcomes and objectively measured functional outcomes. Chad W WagonerPractical Considerations and Consensus Opinion for Children's Hospital-Based Inpatient Hemostasis and Thrombosis (HAT) Consultative Services: Communication from the ISTH SSC Subcommittee on Pediatric and Neonatal Hemostasis and Thrombosis June 24, 2022Caring for children and adolescents with disorders of hemostasis and thrombosis (HAT) has become more specialized and requires a unique skill set that many providers are not able to obtain in standard pediatric hematology/oncology/bone marrow transplant fellowship training programs. The influx of numerous therapeutic advances and increasing medical complexity has expanded the need for experienced […] Gary M WoodsThe Significance of the Ocular Adverse Effect Induced by Systemic Taxane Application June 24, 2022In recent years, in-depth research on anti-tumor therapy has brought the emergence of new active chemotherapeutic agents and combination regimens. However, as one of them, taxane drugs are widely used in clinical practice, but it should be noted that many side reactions caused by their application bring some difficulties to routine management. Among the side […] Ya-Ting YeNanopore Sequencing Technology in Oral Oncology: A Comprehensive Insight June 24, 2022CONCLUSION: The findings will encourage researchers to further adopt NPST in their studies and give an overview of the latest findings of oral squamous cell carcinoma (OSCC) management. To highlight the importance of NPST application in OSCC studies, this paper not only discusses the use of NPST in identifying the behavior of malignancy but also […] Dominic AugustineIncidence and Management of Pleural Effusions in Patients with Wilms Tumor: A Pediatric Surgical Oncology Research Collaborative Study June 24, 2022Wilms tumor (WT) is the most common renal malignancy in children. Children with favorable histology WT achieve survival rates of over 90%. Twelve percent of patients present with metastatic disease, most commonly to the lungs. The presence of a pleural effusion at the time of diagnosis of WT may be noted on staging imaging; however, […] Ameer Al-HadidiComparative risk of pulmonary adverse events with transfusion of pathogen reduced and conventional platelet components June 24, 2022BACKGROUND: Platelet transfusion carries risk of transfusion-transmitted infection (TTI). Pathogen reduction of platelet components (PRPC) is designed to reduce TTI. Pulmonary adverse events (AEs), including transfusion-related acute lung injury and acute respiratory distress syndrome (ARDS) occur with platelet transfusion. Edward L SnyderSciatic Nerve Involvement in Rosai-Dorfman Disease June 24, 2022No abstract Vijay SinghBeneficial Effects of Spiritual Experiences and Existential Aspects of Life Satisfaction of Breast and Lung Cancer Patients in Poland: A Pilot Study June 24, 2022Spiritual and existential issues are important factors for oncology patients' well-being. This study aimed to examine the beneficial role of spiritual experience, hope, and meaning in life for life satisfaction in patients diagnosed with breast and lung cancer. It was hypothesized that spiritual experiences and life satisfaction are indirectly related through hope, as well as […] Marcin WnukMultidisciplinary Approach to Patients With Metastatic Spinal Cord Compression: A Diagnostic Therapeutic Algorithm to Improve the Neurological Outcome June 24, 2022CONCLUSIONS: Metastatic spinal cord compression can cause neurological deficits compromising quality of life. Treatment strategies should be planned comprehensively. A multidisciplinary approach and the application of the proposed algorithm is of paramount importance to optimize the outcomes of these patients. Rossella RispoliA semi-mechanistic dose-finding design in oncology using pharmacokinetic/pharmacodynamic modeling June 24, 2022While a number of phase I dose-finding designs in oncology exist, the commonly used ones are either algorithmic or empirical model-based. We propose a new framework for modeling the dose-response relationship, by systematically incorporating the pharmacokinetic (PK) data collected in the trial and the hypothesized mechanisms of the drug effects, via dynamic PK/PD modeling, as […] Xiao SuMultidisciplinary Team Meeting Proposal and Final Therapeutic Choice in Early Breast Cancer: Is There an Agreement? June 24, 2022CONCLUSION: The results of our study could be useful for enhancing the role of MDMs in the clinical decision-making process in early BC. Lucia BortotGianturco Z-stent vena cava stenting potential complications in oncology June 24, 2022No abstract Mostafa El HajjamCA-125 monitoring in gynecologic cancer patients with COVID-19: A case series June 24, 2022CA-125 has long been utilized as a surveillance biomarker for gynecologic malignancies but can be elevated in other conditions, including infection. A study of tumor markers in non-cancer patients saw a rise in CA-125 values during severe COVID-19 infections. Given the potential confounding effect this could have on surveillance and treatment planning, we sought to […] Susan M FolsomOptimizing Social Support in Oncology with Digital Platforms June 24, 2022Increased cancer prevalence and survival rates coupled with earlier patient discharges from hospitals have created a greater need for social support. Cancer care is both short term and long term, requiring acute treatments, treatments for remission, and long-term screenings and treatment regimens. Health care systems are already overwhelmed and often struggle to provide social support […] Dimos Katsaros
