1. Transcriptome profiling of prostate cancer cells on GLYATL1 knockdown
(Submitter supplied) The protein Glycine-N-Acyltransferase Like 1 (GLYATL1) is involved in detoxification of benzoate and other xenobiotics and is expressed in liver and kidney. Through In silico analysis of cancer gene expression profiling and transcriptome sequencing we revealed an overexpression of GLYATL1 in primary prostate cancer. Confirming these findings by immunohistochemistry we show that GLYATL1 is overexpressed in primary prostate cancer compared to metastatic prostate cancer and benign prostatic tissue. more…
Organism: Homo sapiens
Type: Expression profiling by high throughput sequencing
Platform: GPL18573 4 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE130nnn/GSE130395/
SRA Run Selector: https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA539980
Series Accession: GSE130395 ID: 200130395

2. Molecular Determinants of Post-Mastectomy Breast Cancer Recurrence
(Submitter supplied) Breast cancer (BC) adjuvant therapy after mastectomy in the setting of 1-3 positive lymph nodes has been controversial. This retrospective Translational Breast Cancer Research Consortium study evaluated molecular aberrations in primary cancers associated with locoregional recurrence (LRR) or distant metastasis (DM) compared to non-recurrent controls. We identified 115 HER2 negative, therapy naïve, T 1-3 and N 0-1 BC patients treated with mastectomy but no post-mastectomy radiotherapy. more…
Organism: Homo sapiens
Type: Expression profiling by high throughput sequencing
Platform: GPL11154 131 Samples
FTP download: GEO (TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE119nnn/GSE119937/
SRA Run Selector: https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA490741
Series Accession: GSE119937 ID: 200119937

3. DNA replication-timing boundaries separate stable chromosome domains with cell-type-specific functions
(Submitter supplied) Eukaryotic chromosomes replicate in a temporal order known as the replication-timing program. In mammals, replication timing is cell type-specific with at least half the genome switching replication timing during development, primarily in units of 400-800 kilobases (‘replication domains;), whose positions are preserved in different cell types, conserved between species, and appear to confine long-range effects of chromosome rearrangements. more…
Organism: Homo sapiens; Mus musculus
Type: Other
25 related Platforms 993 Samples
FTP download: GEO (BAM, BED, BIGWIG, BROADPEAK, NARROWPEAK, PAIR, TSV, TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE51nnn/GSE51334/
Series Accession: GSE51334 ID: 200051334

4. NFAT transcriptional activity is associated with metastatic capacity in colon cancer
(Submitter supplied) Colorectal carcinoma is the third leading cause of cancer-related death in the United States. In order to understand the mechanism/signaling pathways responsible for invasion, migration and metastasis in colorectal cancer, we developed an integrative and comparative genetic approach to infer transcriptional regulatory mechanisms underlying colon cancer progression. Accordingly, we filtered fourteen human colorectal cancer (CRC) microarray data sets, from an immune competent mouse model of metastasis to identify known and novel transcriptional regulators in CRC. more…
Organism: Homo sapiens
Type: Expression profiling by array
Platform: GPL570 122 Samples
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE38nnn/GSE38832/
Series Accession: GSE38832 ID: 200038832

5. Open Chromatin by DNaseI HS from ENCODE/OpenChrom(Duke University)
(Submitter supplied) This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Terry Furey mailto:tsfurey@duke.edu). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). These tracks display DNaseI hypersensitivity (HS) evidence as part of the four Open Chromatin track sets. DNaseI is an enzyme that has long been used to map general chromatin accessibility, and DNaseI “hypersensitivity” is a feature of active cis-regulatory sequences. more…
Project: ENCODE
Organism: Homo sapiens
Type: Genome binding/occupancy profiling by high throughput sequencing
Platform: GPL9052 97 Samples
FTP download: GEO (BIGWIG, NARROWPEAK, TXT) ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE32nnn/GSE32970/
SRA Run Selector: https://www.ncbi.nlm.nih.gov/Traces/study/?acc=PRJNA63443
Series Accession: GSE32970 ID: 200032970

6. Patient 108
Organism: Homo sapiens
Source name: University of Alabama at Birmingham
Platform: GPL570 Series: GSE38832
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM950nnn/GSM950518/
Sample Accession: GSM950518 ID: 300950518

7. Patient 105
Organism: Homo sapiens
Source name: University of Alabama at Birmingham
Platform: GPL570 Series: GSE38832
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM950nnn/GSM950515/
Sample Accession: GSM950515 ID: 300950515


8. Patient 101
Organism: Homo sapiens
Source name: University of Alabama at Birmingham
Platform: GPL570 Series: GSE38832
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM950nnn/GSM950511/
Sample Accession: GSM950511 ID: 300950511


9. Patient 100
Organism: Homo sapiens
Source name: University of Alabama at Birmingham
Platform: GPL570 Series: GSE38832
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM950nnn/GSM950510/
Sample Accession: GSM950510 ID: 300950510

10. Patient 98
Organism: Homo sapiens
Source name: University of Alabama at Birmingham
Platform: GPL570 Series: GSE38832
FTP download: GEO (CEL) ftp://ftp.ncbi.nlm.nih.gov/geo/samples/GSM950nnn/GSM950508/
Sample Accession: GSM950508 ID: 300950508